Can MTHFR Gene Mutation Cause Autism?

by | May 1, 2021 | Autism, Autism Recovery, MTHFR | 48 comments

MTHFR gene mutation

Can MTHFR gene mutation cause autism? MTHFR gene mutation is complicated to put in lay-terms for us non-clinicians, but I’ll try to explain it the best way I understand it. Methylenetetrahydrofolate reductase (MTHFR) gene is responsible for methylation, which, amongst other functions, is responsible for detoxification. When the MTHFR gene is altered, such as when a baby is exposed to heavy metals while still in his mother’s womb (in utero), the MTHFR gene is split into variants C677T and A1298C. These variants can cause impaired methylation pathways, which can decrease the body’s ability to excrete heavy metals. The heavy metals are then able to cross the blood-brain barrier (BBB) and become stored in the brain, causing some of the behaviors associated with autism.

I’ve found a good article that explains the MTHFR gene mutation, and how it affects methylation and autism. https://chriskresser.com/methylation-and-autism/ The author goes on to explain that environmental toxins such as mercury, aluminum, lead and arsenic have a huge impact on methylation and autism, stating “In utero exposure to heavy metals alters methylation of genes and is associated with an increased risk of autism.”

Another good article that was relatively easy to understand https://www.sciencedirect.com/science/article/pii/S0753332218374407. This author stated “nowadays genetic variations in some genes involving in the metabolism and detoxification of metals are considered as new contributing factors in sensitivity of individuals to heavy metal induced toxicity”.

A brief history of my son, Luke: He was born a twin. They were delivered in an emergency C-section six weeks early because his twin developed a bleed in his brain. His twin weighed two pounds, and was badly damaged; his part of the placenta was in shreds, according to his doctors. The doctors were baffled as to what had caused this, and what was wrong with him. We did the only compassionate thing we could do at the time: we took Luke’s twin off of the ventilator and let him die in peace.

Luke was totally non-verbal, and his behavior became out of control. We took him to a developmental pediatrician when he was three, who slapped an autism label on him, despite my protests that it had to be something medical wrong with him, since his twin was so badly damaged. The doctor brushed me off. I finally figured out when Luke was seven that the environment had killed his twin, and the environment was responsible for what was going on with Luke. I got him treated for heavy metals toxicity, but the heavy metals had already done their damage. If I had gotten Luke treated as soon as I realized there was a problem it would have saved years of heartache and health problems for him.

You can read the entire story of Luke and how he went from being an out-of-control child, with talk of institutions whispered behind hands, to an independent, happy and healthy adult holding down a great job. https://www.scarlettsouthauthor.com/ Order it off my website and I’ll ship it for free!

So how do I find out if my child has the MTHFR gene mutation?

     1. You can get your child tested for the MTHFR gene mutation through your doctor. The genetics test last time I checked was around $800, and insurance covered it. The great thing about this test is that the results are confidential between you and your doctor. A third-party would not have access to the results.

2. You can get your child tested for the MTHFR gene mutation through 23andMe. The last time I checked it was around $100 for the kit. From what I understand, though, third-parties such as law enforcement, insurance companies and pharmaceutical companies have access to the test results.

What do I do if I find out my child has the MTHFR gene mutation?

     1. The first thing I would do would be to find a practitioner knowledgeable about MTHFR gene mutation and how to treat it. Your practitioner will probably want to add folate and B12 to your child’s diet, since the MTHFR gene mutation means that your child will most likely be deficient in these nutrients that are crucial in methylation, or detoxification.

2. I would strongly consider detoxifying my child for heavy metals, since having the MTHFR gene mutation means that most likely the child has heavy metals accumulated in the soft tissues, such as the brain, bones and liver. Starting off with a gentle detoxifier that doesn’t remove critical nutrients, such as zeolite clinoptilolite or TRS spray, would be a great start until you can find a qualified provider.

Understanding about MTHFR gene mutation, and implementing measures to remove heavy metals from your child’s body and environment, can be the difference between a lifetime of dependency on the child’s caregiver or independence as an adult. And the sooner we start the detoxification process for our child, the faster he’ll be racing toward that goal of independence as an adult!

 

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scarlett

Scarlett South is a registered nurse, an autism specialist and the author of Autistic or Toxic? How I Unlocked the Mystery of My Son's "Autism." But her proudest achievement is her adult son, whom was once considered severely autistic, with talks of being placed in an institution, and whom is now an independent and productive member of society! Scarlett is based in Florida.
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